Wellcome uses cookies.

Read our policy
Wellcome Collection homepage
All
Stories
Images
Catalogue
Events
1,121 results
  • Solanum atropurpureum Schrank Solanaceae. Purple Devil. Purple-spined Nightshade. Herbaceous perennial. Distribution: Brazil. This ferociously spined plant contains tropane alkaloids, atropine, hyoscyamine and scopolamine. All are anticholinergic and block the acetylcholine mediated actions of the parasympathetic nervous system. While the alkaloids are used in medicine and as an antidote to anticholinergic nerve gas poisons, the plant itself is not used in medicine. Its sharp spines can be irritant. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Trillium sessile L. Trilliaceae Distribution: North America. Various Trilliums were used by Native Americans to stop haematuria, haematemesis, menorrhagia, and to heal ulcers (Milspaugh, 1974). Roots were eaten to treat stiff muscles, and tea from the plant drunk and powdered plant put on joints for rheumatism by the Iroquois (Lewis & Elvin-Lewis, 2003). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Astrantia maxima Pall. Apiaceae. Large masterwort. The botanical name Astrantia is a corruption of the old apothecaries’ name for this plant, Magistrantia “masterwort”, implying its suitability for use only by adepts in herbalism. Probably mildly poisonous. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • [Leaflet advertising Modern Health's range of 11 plant based medicines].
  • [Leaflet advertising Modern Health's range of 11 plant based medicines].
  • [Leaflet advertising Modern Health's range of 11 plant based medicines].
  • [Leaflet advertising Modern Health's range of 11 plant based medicines].
  • [Leaflet advertising Modern Health's range of 11 plant based medicines].
  • [Leaflet advertising Modern Health's range of 11 plant based medicines].
  • Acacia melanoxylon R.Br. Mimosaceae. Australian Blackwood. Tree. Distribution: Eastern Australia. Tree. Invasive weed in South Africa, Portugal, California. Local uses: analgesic. Causes allergic contact dermatitis due to 2,6,dimethoxybenzoquinone. Pinnate leaves of young plant drop off and phylloclades are formed instead. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Cistus incanus ssp creticus Juss. Cistaceae. Rock Rose. Distribution: Crete. Interesting symbiosis with fungus called Tuber melanosporum which increases nutrient absorption for the plant and inhibits growth of other plants in the vicinity. It is a source of the resin ‘labdanum’ (a.k.a. ‘ladanum’) used in perfumes (similar smell to ambergris), as is Cistus ladanifer. It has no medical uses now, and such use was dwindling even in the 18th century. In the 16th century (Henry Lyte’s 1575 translation of Rembert Dodoen’s Cruydeboeck of 1554) its uses were described (directly copied from Dioscorides’ Materia Medica (70AD)) as: ‘Ladanum dronketh with olde wine, stoppeth the laske [periods], and provoketh urine. It is very good against the hardness of the matrix or mother [uterus] layde to in the manner of a pessarie, and it draweth down the secondes or afterbirth, when it is layde upon quicke coles [hot coals], and the fumigation or parfume thereof be received up into the body of women. // The same applied to the head with Myrrhe and oyle of Myrrhe, cureth the scurffe, called Alopecia, and keepeth the heare [hair] from falling of [sic], but whereas it is already fallen away, it will not cause the heare to growe agayne. // ...' and goes on in this vein about its uses for pain in the ears, and removing sores and scars and other things. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Origanum dictamnus L. Lamiaceae Dittany of Crete, Hop marjoram. Distribution: Crete. Culpeper (1650) writes: ‘... hastens travail [labour] in women, provokes the Terms [menstruation] . See the Leaves.’ Under 'Leaves' he writes: ‘Dictamny, or Dittany of Creet, ... brings away dead children, hastens womens travail, brings away the afterbirth, the very smell of it drives away venomous beasts, so deadly an enemy is it to poison, it’s an admirable remedy against wounds and Gunshot, wounds made with poisoned weapons, draws out splinters, broken bones etc. They say the goats and deers in Creet, being wounded with arrows, eat this herb, which makes the arrows fall out of themselves.' Dioscorides’ Materia Medica (c. 100 AD, trans. Beck, 2005), Pliny the Elder’s Natural History and Theophrastus’s Enquiry into Plants all have this information, as does Vergil’s Aeneid where he recounts how Venus produced it when her son, Aeneas, had received a deadly wound from an arrow, which fell out on its own when the wound was washed with it (Jashemski, 1999). Dioscorides attributes the same property to ‘Tragium’ or ‘Tragion’ which is probably Hypericum hircinum (a St. John’s Wort): ‘Tragium grows in Crete only ... the leaves and the seed and the tear, being laid on with wine doe draw out arrow heads and splinteres and all things fastened within ... They say also that ye wild goats having been shot, and then feeding upon this herb doe cast out ye arrows.’ . It has hairy leaves, in common with many 'vulnaries', and its alleged ability to heal probably has its origin in the ability of platelets to coagulate more easily on the hairs (in the same way that cotton wool is applied to a shaving cut to hasten clotting). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Acanthus spinosus L. Acanthaceae. Bears breeches. Distribution: Southern Europe to Western Turkey. Herbaceous perennial flowering plant. Named for spiny leaves. Dioscorides recommended the roots applied for inflammation and spasms, and -when drunk- to promote urine, check diarrhoea, and for phthysis, ruptures and convulsions. The leaves are the model for those at the top of Corinthian columns. Tetraglycosides isolated from the plant show cytotoxicity in sea urchin eggs and crown gall tumour on potato disks. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Skimmia japonica Thunb. Rutaceae 'Rubella' Distribution: China, Japan and E. Asia. The genus name is derived from the Japanese word shikimi (Stearn, 1994). All parts of the plant are poisonous, containing skimmianin. It is said to cause vomiting and, if eaten in large quantities, cardiac arrest. (Duke, 1985) Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Justicia carnea Lindl. Acanthaceae. Brazilian Plume flower, Flamingo flower. Shrimp plant. Tender shrub. Distribution: Atlantic coast of Brazil. Named for James Justice (1698-1753) Scottish horticulturist, lawyer, 'tulip maniac' (Desmond, 1977). Asian species of Justicia are noted to be toxic and contain cytotoxic compounds which inhibit virus replication (Wiart, 2006) Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Asphodeline lutea Rchb. Yellow asphodel, King's spear, Hastula regia. Hardy rhizomatous perennial. Distribution Mediterranean and Caucasus. It is the flower of the dead, as Homer writes that it carpets an area in the gloomy darkness of the underworld (Hades), in Greek mythology where the souls of the dead are found. However this may be a misinterpretation of the Greek where 'Asphodel' has been read instead of 'ash-filled'. In the etymology of flower names, it is suggested that the yellow 'daffodil' is a corruption of French or Flemish 'de asphodel' (both ex Steve Reece, 2007). An Aristotelian epigram, refers to it growing on tombs: 'On my back I hold mallow and many-rooted asphodel ...' The asphodel was sacred to Persephone, goddess of the underworld, who was seized and wed by Hades, god of the underworld, and taken to his kingdom. Her disappearance brings the winter, and her reappearance each year, the spring. The only reliable source of information about its early medical uses is, probably, Dioscorides although the plant in his De Materia Medica may be A. ramosus or A. albus. He gives its properties as diuretic, induces menses, good for coughs and convulsions, an antidote to snake bite, applied as a poultice for sores of all sorts, and in compounds for eye, ear and tooth pains, and to cure alopecia and vitiligo, but induces diarrhoea and vomiting and is an anti-aphrodisiac. Fuchs (1542), as Ruel’s commentaries (1543) note, makes a big mistake as he has Lilium martagon as his concept of A. luteus. Ruel only illustrates its leaves and roots, calling it Hastula regia (Latin for King’s spear) but Matthiolus's Commentaries (1569 edition) has a reasonable woodcut also as Hastula regia (1569). Dodoen's Cruydeboeck (1556) does not mention or illustrate Asphodelus luteus. L'Escluse's French translation Histoire des Plantes (1557) follows the Cruydeboeck. Dodoen's Latin translation Stirpium Historia Pemptades Sex (1583) adds A. luteus with text and woodcut, with no uses. Henry Lyte's (1578) translation illustrates Asphodelus luteus as Asphodeli tertia species and 'Yellow affodyl' (vide etymology of 'daffodil') and also does not describe any uses for it. Gerard's translation The Herbal (1597 and 1633) continues the muddle and does not give any uses for this plant. Parkinson's comments (1640) on the lack of medicinal properties of asphodels, refer to quite different plants coming from wet areas in Lancashire, Scotland and Norway . He calls them pseudoasphodelus major and minor which he writes are called Asphodelus luteus palustris by Dodoens, and not 'King's Spear' which he illustrates with a good woodcut of A. luteus and calls it Asphodelus luteus minor. Once herbals started to be written in northern Europe, the knowledge of the arid loving, Asphodelus luteus of south east Europe was lost. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Hypericum olympicum L. Clusiaceae. Mount Olympus St John's wort. Deciduous perennial herb. Distribution Greece, Asia minor. This is not the plant used for mood disturbances in herbal medicine which is Hypericum perforatum. However, all the 370 species of Hypericum are called 'St John's Wort' so a potential for confusion exists. It shares some of the chemicals thought to be active in Hypericum perforatum. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Gloriosa superba L. Colchicaceae Gloriosa lily. Gloriosa rothschildiana is now a synonym. Climbing plant. Distribution: Southern Africa to Asia. National flower of Zimbabwe, state flower of Tamil Nadu. Contains colchicine which is poisonous, teratogenic and used for treating gout, Familial Mediterranean fever and Behcet's disease. Its toxicity limits its use as a anti-cancer agent. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Gloriosa superba L. Colchicaceae Gloriosa lily. Gloriosa rothschildiana is now a synonym. Climbing plant. Distribution: Southern Africa to Asia. National flower of Zimbabwe, state flower of Tamil Nadu. Contains colchicine which is poisonous, teratogenic and used for treating gout, Familial Mediterranean fever and Behcet's disease. Its toxicity limits its use as a anti-cancer agent. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Rudbeckia triloba L. Asteraceae Orange Cone flower. Herbaceous perennial. Distribution: North America. It is named for Olof Rudbeck, father (1630–1702) and son (1660–1740). Olof Rudbeck the Elder was professor of medicine at Uppsala University, and established a botanic garden there. He was the discoverer of the human lymphatic system. His son succeeded his father as professor of medicine, and one of his students was Carl Linnaeus (1707–88) who named the genus Rudbeckia after him and his father. It is a plant which is poisonous to cattle, sheep and pigs with no medicinal uses. Austin (1974) discusses R. hirta, also regarded as a toxic plant. It was used externally by the Cherokee to bathe sores and snakebites and made into a tea for treating diarrhoea. The Seminoles used it for headaches and fever and the Miccosukee for sunstroke and headache. The Cherokee and the Iroquois used it to treat intestinal worms Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Polygonatum x hybridum Brugger Convalliariaceae. Hybrid Solomon's Seal (P. multiflorum x P. odoratum) It has the RHS Award of Garden Merit. Rhizomatous herbaceous perennial. Distribution: Garden plant whose parents come from Europe and Asia. Dioscorides (70 AD ex Beck, 2005) reports that Polygonatum is good for wounds if a poultice is applied, and that it also removes facial blemishes. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Colchicum autumnale L., Colchicaceae. Autumn crocus, meadow saffron, naked ladies. Distribution: Europe. Extremely toxic, containing colchicine which is effective in small doses in treating gout. It inhibits mitosis so is of interest in cancer treatment. It is used to treat Familial Mediterranean fever. It induces polyploidy in plant protocorms for the production of tetraploid forms which have bigger flowers and seeds. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Atropa belladonna L. Solanaceae. Deadly nightshade. Dwale. Morella, Solatrum, Hound's berries, Uva lupina, Cucubalus, Solanum lethale. Atropa derives from Atropos the oldest of the three Fates of Greek mythology who cut the thread of Life (her sisters Clotho and Lachesis spun and measured the thread, respectively). belladonna, literally, means 'beautiful lady' and was the Italian name for it. Folklore has it that Italian ladies put drops from the plant or the fruits in their eyes to make themselves doe-eyed, myopic and beautiful. However, this is not supported by the 16th and 17th century literature, where no mention is ever made of dilated pupils (or any of the effects of parasympathetic blockade). Tournefort (1719) says 'The Italians named this plant Belladonna, which in their language signifies a beautiful woman, because the ladies use it much in the composition of their Fucus [rouge or deceit or cosmetic] or face paint.' Parkinson says that the Italian ladies use the distilled juice as a fucus '... peradventure [perhaps] to take away their high colour and make them looke paler.' I think it more likely that they absorbed atropine through their skin and were slightly 'stoned' and disinhibited, which made them beautiful ladies in the eyes of Italian males. Distribution: Europe, North Africa, western Asia. Culpeper (1650) writes: 'Solanum. Nightshade: very cold and dry, binding … dangerous given inwardly … outwardly it helps the shingles, St Antonie's Fire [erysipelas] and other hot inflammation.' Most of the 16th, 17th and 18th century herbals recommend it topically for breast cancers. Poisonous plants were regarded as 'cold' plants as an excess of them caused death and the body became cold. They were regarded as opposing the hot humour which kept us warm and alive. Poultices of Belladonna leaves are still recommended for muscle strain in cyclists, by herbalists. Gerard (1633) writes that it: 'causeth sleep, troubleth the mind, bringeth madnesse if a few of the berries be inwardly taken, but if more be taken they also kill...'. He was also aware that the alkaloids could be absorbed through the skin for he notes that a poultice of the leaves applied to the forehead, induces sleep, and relieves headache. The whole plant contains the anticholinergic alkaloid atropine, which blocks the peripheral actions of acetylcholine in the parasympathetic nervous system. Atropine is a racemic mixture of d- and l- hyoscyamine. Atropine, dropped into the eyes, blocks the acetylcholine receptors of the pupil so it no longer constricts on exposure to bright light - so enabling an ophthalmologist to examine the retina with an ophthalmoscope. Atropine speeds up the heart rate, reduces salivation and sweating, reduces gut motility, inhibits the vertigo of sea sickness, and is used to block the acetylcholine receptors to prevent the effects of organophosphorous and other nerve gas poisons. It is still has important uses in medicine. Atropine poisoning takes three or for days to wear off, and the hallucinations experienced by its use are described as unpleasant. We have to be content with 'madness', 'frenzie' and 'idle and vain imaginations' in the early herbals to describe the hallucinations of atropine and related alkaloids as the word 'hallucination' in the sense of a perception for which there is no external stimulus, was not used in English until 1646 (Sir T. Browne, 1646). It is a restricted herbal medicine which can only be sold in premises which are registered pharmacies and by or under the supervision of a pharmacist (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Paris quadrifolia L. Trilliaceae Herb Paris Distribution: Europe and temperate Asia. This dramatic plant was known as Herb Paris or one-berry. Because of the shape of the four leaves, resembling a Burgundian cross or a true love-knot, it was also known as Herb True Love. Prosaically, the name ‘Paris’ stems from the Latin ‘pars’ meaning ‘parts’ referring to the four equal leaves, and not to the French capital or the lover of Helen of Troy. Sixteenth century herbalists such as Fuchs, who calls it Aconitum pardalianches which means leopard’s bane, and Lobel who calls it Solanum tetraphyllum, attributed the poisonous properties of Aconitum to it. The latter, called monkshood and wolfsbane, are well known as poisonous garden plants. Gerard (1633), however, reports that Lobel fed it to animals and it did them no harm, and caused the recovery of a dog poisoned deliberately with arsenic and mercury, while another dog, which did not receive Herb Paris, died. It was recommended thereafter as an antidote to poisons. Coles (1657) wrote 'Herb Paris is exceedingly cold, wherupon it is proved to represse the rage and force of any Poyson, Humour , or Inflammation.' Because of its 'cold' property it was good for swellings of 'the Privy parts' (where presumably hot passions were thought to lie), to heal ulcers, cure poisoning, plague, procure sleep (the berries) and cure colic. Through the concept of the Doctrine of Signatures, the black berry represented an eye, so oil distilled from it was known as Anima oculorum, the soul of the eye, and 'effectual for all the disease of the eye'. Linnaeus (1782) listed it as treating 'Convulsions, Mania, Bubones, Pleurisy, Opththalmia', but modern authors report the berry to be toxic. That one poison acted as an antidote to another was a common, if incorrect, belief in the days of herbal medicine. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Catharanthus roseus (L.)G.Don Apocynaceae. Madagascar Periwinkle Distribution: Madagascar. It is the source of vincristine and vinblastine, which impair cell multiplication by interfering with microtubule assembly, causing metaphase arrest and are effective medications for leukaemias, lymphomas and some solid tumours. The mortality from childhood leukaemia fell from 100% to 30% once it was introduced - not a drug that could ethically be tested by double-blind trials. These chemicals were initially discovered by investigators in 1958 who were looking for cures for diabetes so tested this plant which was being used in the West Indies to reduce blood sugar levels. There are 70 different alkaloids present in this plant, and some - catharanthine, leurosine sulphate, lochnerine, tetrahydroalstonine, vindoline and vindolinine - lower blood sugar levels. However, the toxicity of this plant is such that this is not a plant to try at home for diabetic management. The vincristine content of the plant is 0.0003%, so two kilograms of leaf are required to produce sufficient vincristine for a single course of treatment for a child (6gm). Fortunately it is a vigorous weed and easy to grow in the tropics. Artificial synthesis has now been achieved. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Danae racemosa (L.) Moench Asparagaceae. Alexandrian or Poet's laurel. Distribution: Turkey to Iran. A monotypic genus with supreme adaptation to dry conditions, bearing its flowers and fruits on phylloclades, leaf like expanded stems. The phylloclades are too thick for sunlight to pass through so have chlorophyll containing cells on both sides (the cells in the middle do not) and stomata on both sides to facilitate CO2 diffusion into the plant. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Reseda lutea L. Resedaceae Wild Mignonette. Dyers Rocket. Herbaceous plant. Distribution: Eurasia and North Africa. This plant, and in particular R. luteola, is the source of 'weld' a yellow dye from luteolin a flavonoid in the sap. It is said to have been used since the first millennium BC, but curiously Dioscorides, Lyte, Gerard, Lobel, Fuchs, Coles, Quincy, Linnaeus (1782) either do not mention it or make it synonymous with Eruca, Rocket, and make no reference to it as a dye source. The name Resedo means 'I sit up' in Latin, which Stearn (1994) interprets as 'I heal' which makes its absence even more strange. It is noted as the dye source by Bentley (1861). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Silphium perfoliatum L. Asteraceae Indian Cup. Distribution: North America. Austin (2004) records that another species, S. compositum, was used by Native Americans to produce a chewing gum from the dried sap of the roots, and Native American medicinal uses for 'Indian Cup' are probably referrable to S. compositum and not S. perfoliatum. Silphium perfoliatum contains enzymes that inhibit trypsin and chymotrypsin which gives it resistance to fungal, bacterial and insect attacks. Male gall wasps (Antisotrophus rufus) alter the chemistry of the plant to enable them to locate females, making it a 'signpost' plant. The gall wasp lays its eggs in the stem of Silphium laciniatum, to provide food for the larva on emergence, and the galls containing a male or a female wasp will cause the plant to give off a different chemical odour. Emerging male wasps can search for female wasps, which emerge later, by locating this chemical fragrance which acts as a sex pheromone proxy (Tooker et al Proc Natl Acad Sci U S A. 2002 Nov 26
  • Ornithogalum umbellatum L. Hyacinthaceae Star of Bethlehem, Grass lily. Distribution: Central Europe, SW Asia, NW Africa. All parts are poisonous, especially the bulbs. The toxin is a cardiac glycoside with effects similar to digoxin, vomiting, cardiac irregularities and death in humans and livestock. Only used for decoration by Native Americans (it is a non-native plant that has escaped into the wild from cultivation) and called Sleepydick (Moerman, 1998). One of its toxins is Convallotoxin, also present in Lily of the Valley, Convallaria majalis. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Cynoglossum officinale L. Boraginaceae. Houndstongue. Distribution: Europe. Culpeper (1650) writes: “... being roasted and laid to the fundament, helps the haemorrhoids. It is also good against burnings and scaldings.” It contains hepatocarcinogenic pyrrolizidine alkaloids and while people are known to eat the young leaves as a vegetable, this is inadvisable. The whole plant is hairy and may cause contact dermatitis. The use of herbal remedies, which contain these alkaloids, by the Bantu of southern Africa correlates with their high incidence of tumours of the liver and pancreas. Photographed in the Medicinal Garden of the Royal College of Physicians, London.